Affects the heart and blood vessels and may cause fatal complications such as coronary artery disease (leading to a heart attack) and stroke. Approximately 75 percent of people with diabetes will die of heart disease or stroke, and they are likely to die at a younger age than people who do not have diabetes. High blood pressure, high cholesterol, high blood glucose and other risk factors contribute to increasing the risk of cardiovascular complications.
Each year 12,000 to 24,000 people lose their sight because of diabetes. Consistently high levels of blood glucose, together with high blood pressure and high cholesterol, are the main causes of retinopathy. Diabetes can damage the blood vessels of the retina (diabetic retinopathy), potentially leading to blindness. Diabetes also increases the risk of other serious vision conditions, such as cataracts and glaucoma. It can be managed through regular eye checks and keeping glucose and lipid levels at or close to normal.
About 60 to 70 percent of people with diabetes have mild to severe forms of diabetes-related nerve damage which can lead to lower limb amputations. Diabetes can cause damage to the nerves throughout the body when blood glucose and blood pressure are too high. This can lead to problems with digestion, erectile dysfunction, and many other functions. Among the most commonly affected areas are the extremities, in particular the feet. Nerve damage in these areas is called peripheral neuropathy, and can lead to pain, tingling, and loss of feeling. Loss of feeling is particularly important because it can allow injuries to go unnoticed, leading to serious infections and possible amputations. People with diabetes carry a risk of amputation that may be more than 25 times greater than that of people without diabetes. However, with comprehensive management, a large proportion of amputations related to diabetes can be prevented. Even when amputation takes place, the remaining leg and the person’s life can be saved by good follow-up care from a multidisciplinary foot team. People with diabetes should regularly examine their feet.
Women with any type of diabetes during pregnancy risk a number of complications if they do not carefully monitor and manage their condition. To prevent possible organ damage to the fetus, women with Type 1 or Type 2 diabetes should achieve target glucose levels before conception. All women with diabetes during pregnancy, Type 1, Type 2 or gestational should strive for target blood glucose levels throughout to minimize complications. High blood glucose during pregnancy can lead to the fetus putting on excess weight. This can lead to problems in delivery, trauma to the child and mother, and a sudden drop in blood glucose for the child after birth. Children who are exposed for a long time to high blood glucose in the womb are at higher risk of developing diabetes in the future.
10 to 21 percent of all people with diabetes develop kidney disease. Diabetic nephropathy is the leading cause of end-stage renal disease (kidney failure), accounting for 43 percent of new cases. The kidneys contain millions of tiny blood vessel clusters (glomeruli) that filter waste from the blood. Diabetes can damage this delicate filtering system. Kidney failure requires the patient to undergo dialysis or a kidney transplant in order to live. Maintaining near normal levels of blood glucose and blood pressure can greatly reduce the risk of kidney disease.
Cavities and gum disease
Whether you have type 1 diabetes or type 2 diabetes, managing your blood sugar level is the key. The higher your blood sugar level, the higher your risk of:
Tooth decay (cavities). Your mouth naturally contains many types of bacteria. When starches and sugars in food and beverages interact with these bacteria, a sticky film known as plaque forms on your teeth. The acids in plaque attack the hard, outer surface of your teeth (enamel). This can lead to cavities. The higher your blood sugar level, the greater the supply of sugars and starches - and the more acid wearing away at your teeth.
Early gum disease (gingivitis). Diabetes reduces your ability to fight bacteria. If you don't remove plaque with regular brushing and flossing, it'll harden under your gumline into a substance called tartar (calculus). The longer plaque and tartar remain on your teeth, the more they irritate the gums. In time, your gums become swollen and bleed easily.
Advanced gum disease (periodontitis). Left untreated, gingivitis can lead to a more serious infection called periodontitis, which destroys the soft tissue and bone that support your teeth. Eventually, periodontitis causes your gums to pull away from your teeth and your teeth to loosen and even fall out. Periodontitis tends to be more severe among people who have diabetes because diabetes lowers the ability to resist infection and slows healing. An infection such as periodontitis may also cause your blood sugar level to rise, which makes your diabetes more difficult to control. Preventing and treating periodontitis can help improve blood sugar control.